Sping™
Sping™ is a medical device designed in London, United Kingdom. The Sping™ introduces a patented technology that allows an optimized fat microfragmentation leading to the highest yield of stem-cells in a Stromal Vascular Fraction (SVF) ever seen in such devices. The world’s leading scientists in the field worked together for two years to develop, design, patent, and market the ultimate solution facilitating the extraction of the stromal fraction from adipose tissue previously harvested and can be utilized in various medical fields, including orthopedic surgery, arthroscopic surgery, urological surgery, general surgery, gynecological surgery, thoracic surgery, and laparoscopic surgery as well as plastic and reconstructive surgery for achieving desired aesthetic contouring.
The Sping™ Real Advantage
One of the chief reasons ADRCs treatments are not widely available is the cost and regulatory burden involved in their obtaintion for clinical use. The most common method through which ADRCs are currently isolated is enzymatic digestion. However, this form of isolation causes qualifies ADRCs to be included in the same strenuous regulatory pathway as a “drug”. Moreover, the automated enzymatic digestion methods are expensive and might impact on safety and efficacy, other than potentially causing stem cell differentiation. For instance, collagenase, an enzyme commonly used in many procedures in ADRCs isolation is shown to induce a local inflammatory reaction by activating the human complement system.
Various other isolation methods have been suggested in the literature as alternatives to enzymatic digestion/isolation. Fraser et al. (2014) mentioned the usage of ultrasound energy, however an extremely poor efficiency of cell extraction was observed. Mechanical isolation could be an ideal option even when compared to an enzymatic isolation that can lead twelve times higher mean cell yield. However, augmenting non-enzymatically isolated ADRCs with platelet rich plasma (PRP) could overcome the increased need for adipose tissue extraction but more research is needed with regards to this procedure.
The Sping™ is specifically designed to reduce the size of the harvested adipose tissue size in order to facilitate the future collection of the stromal fraction.
Autologous fat is harvested from patient without the need of general anesthesia. The fat tissue is mechanically separated using the Sping™ in closed sterile system. The SVF is separated and applied to the patient or used to super charge a fat grafting if needed.
All other mechanical methods for SVF isolation deliver lower cell yields per cc of lipoaspirate processed in comparison to the Sping™. Moreover, the Sping™ is the only device capable of demonstrating cell survival in culture after the processing. In all other methods of mechanical separation available in the market, ADRCs extracted die in the following 12 hours.
The Sping™ is the new state-of-the-art mechanical separation device for the isolation of SVF from lipoaspirate.